“This book focuses on the boy Charles Wallace, his sister Meg, and Calvin O’Keefe, and their battle against creatures of nothingness called Ecothroi. The Ecothroi are trying to kill Charles Wallace by stopping the farandole inside the mitochondria of his cells from being able to produce energy and Meg must find a way to save him. A cherubim comes to their aid and helps Meg discover a way to battle the nothingness with life and light. This book is a great and thrilling read, a little on the scientific side; it delves into a story about creatures that live inside the microscopic energy producing organ inside a cell. This would be a good book to read at the same time as a cell unit to tie the ideas together. I would recommend this book as a read aloud, individual read, or even a class read depending on the reading strengths of my students. ”