Born Frances Eliza Hodgson in Cheetham Hill, Manchester, her father died in 1854, and the family had to endure poverty and squalor in the Victorian slums of Manchester.
She emigrated to Knoxville, Tennessee in the United States in 1865.
Following the death of her mother in 1867, an 18-year-old Frances was now the head of a family of four younger siblings. She turned to writing to support them all, with a first story published in Godey's Lady's Book in 1868.
She married Dr. Swan Burnett of Washington, D.C. in 1873.
Her first novel was published in 1877; That Lass o' Lowrie's was a story of Lancashire life.
In 1898 she divorced Dr. Burnett. She later re-married, this time to Stephen Townsend (1900), her business manager. Her second marriage would last less than two years, ending in 1902.
Frances Hodgson Burnett lived for the last 17 years of her life in Plandome, New York. She is buried in Roslyn Cemetery nearby, next to her son Vivian. A life-size effigy of Lionel stands at their feet.